Using absorption models for insulin and carbohydrates and deep leaning to improve glucose level predictions

This article belongs to the Special Issue Sensors, Systems, and AI for Healthcare.Diabetes is a chronic disease caused by the inability of the pancreas to produce insulin or problems in the body to use it efficiently. It is one of the fastest growing health challenges affecting more than 400 million people worldwide, according to the World Health Organization. Intensive research is being carried out on artificial intelligence methods to help people with diabetes to optimize the way in which they use insulin, carbohydrate intakes, or physical activity. By predicting upcoming levels of blood glucose concentrations, preventive actions can be taken. Previous research studies using machine learning methods for blood glucose level predictions have mainly focused on the machine learning model used. Little attention has been given to the pre-processing of insulin and carbohydrate signals in order to mimic the human absorption processes. In this manuscript, a recurrent neural network (RNN) based model for predicting upcoming blood glucose levels in people with type 1 diabetes is combined with several carbohydrate and insulin absorption curves in order to optimize the prediction results. The proposed method is applied to data from real patients suffering type 1 diabetes mellitus (T1DM). The achieved results are encouraging, obtaining accuracy levels around 0.510 mmol/L (9.2 mg/dl) in the best scenario.This work was supported in part by the project "ANALISIS EN TIEMPO REAL DE SEN-SORES SOCIALES Y ESTIMACION DE RECURSOS PARA TRANSPORTE MULTIMODAL BASADA EN APRENDIZAJE PROFUNDO" MaGIST-RALES, funded by the Spanish Agencia Estatal de Investi-gación (AEI, doi 10.13039/501100011033) under grant PID2019-105221RB-C44/AEI/10.13039/501100011033

Percepción del grado de madurez en la gestión de proyectos de la empresa Fidacorp Colombia S.A.S.

Trabajo de investigaciónEl presente documento tiene como finalidad analizar, dar conocer y evaluar la percepción del grado de madurez en la Gestión de Proyectos implementando el modelo organizacional de la norma ISO 21500 en la empresa constructora FIDACORP COLOMBIAS.A.S, la cual es una organización dedicada a la investigación y desarrollo experimental en el campo de las ciencias naturales y la ingeniería.INTRODUCCION 1. GENERALIDADES 2. MARCOS DE REFERENCIA 3. METODOLOGIA 4. ANALISIS Y PROCESOS DE RESULTADOS 5. PROPUESTA PARA MEJORAR GRADO DE MADUREZ EN GESTION DE PROYECTOS EN LA EMPRESA FIDACORP COLOMBIA S.A.S. 6. CONCLUSIONES Y RECOMENDACIONES 7. BIBLIOGRAFIA 8. ANEXOSEspecializaciónEspecialista en Gerencia de Obras Civile

Patterns and Trends in Chlorophyll-a Concentration and Phytoplankton Phenology in the Biogeographical Regions of Southwestern Atlantic

The Southwestern Atlantic Ocean (SWA), is considered one of the most productive areas of the world, with a high abundance of ecologically and economically important fish species. Yet, the biological responses of this complex region to climate variability are still uncertain. Here, using 24 years of satellite-derived Chl-a data, we classified the SWA into 9 spatially coherent regions based on the temporal variability of Chl-a concentration, as revealed by SOM (Self-Organizing Maps) analysis. These biogeographical regions were the basis of a regional trend analysis in phytoplankton biomass, phenological indices, and environmental forcing variations. A general positive trend in phytoplankton concentration was observed, especially in the highly productive areas of the northern shelf-break, where phytoplankton biomass has increased at a rate of up to 0.42 ± 0.04 mg m−3 per decade. Significant positive trends in sea surface temperature were observed in 4 of the 9 regions (0.08–0.26 °C decade−1) and shoaling of the mixing layer depth in 5 of the 9 regions (−1.50 to −3.36 m decade−1). In addition to the generally positive trend in Chl-a, the most conspicuous change in the phytoplankton temporal patterns in the SWA is a delay in the autumn bloom (between 15 ± 3 and 24 ± 6 days decade−1, depending on the region). The observed variations in phytoplankton phenology could be attributed to climate-induced ocean warming and extended stratification period. Our results provided further evidence of the impact of climate change on these highly productive waters.Fil: Delgado, Ana Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto Argentino de Oceanografía. Universidad Nacional del Sur. Instituto Argentino de Oceanografía; Argentina. Universidad Nacional del Sur. Departamento de Geografía y Turismo; ArgentinaFil: Hernández Carrasco, Ismael. Consejo Superior de Investigaciones Científicas. Instituto Mediterráneo de Estudios Avanzados; EspañaFil: Combes, Vincent. Consejo Superior de Investigaciones Científicas. Instituto Mediterráneo de Estudios Avanzados; España. Universitat de Les Illes Balears; EspañaFil: Font Muñoz, Joan. Consejo Superior de Investigaciones Científicas. Instituto Mediterráneo de Estudios Avanzados; EspañaFil: Pratolongo, Paula Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; Argentina. Universidad Nacional del Sur. Departamento de Geografía y Turismo; ArgentinaFil: Basterretxea, Gotzon. Consejo Superior de Investigaciones Científicas. Instituto Mediterráneo de Estudios Avanzados; Españ

Furfural Hydrogenation on Modified Niobia

[EN] In this study, niobia-based materials have been used as supports for Pt nanoparticles and used in the hydrogenation of furfural. The incorporation of dopants (W6+ and Ti4+) in the Nb2O5 structure induced modifications in the surface acidity of the support; in particular, the addition of W6+ increased the amount of Lewis acid sites, while the addition of Ti4+ decreased the number of Lewis acid sites. As a result, the catalytic activity towards the hydrogenation of furfural was affected; high surface acidity resulted in high catalytic activity. The selectivity of the reaction changed with the support acidity as well, with higher amount of furfuryl alcohol produced decreasing the Lewis acid sites.Jouve, A.; Cattaneo, S.; Delgado-Muñoz, D.; Scotti, N.; Evangelisti, C.; López Nieto, JM.; Prati, L. (2019). Furfural Hydrogenation on Modified Niobia. Applied Sciences. 9(11):1-14. https://doi.org/10.3390/app9112287S114911Binder, J. B., & Raines, R. T. (2009). 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Improving stability of Nb2O5 catalyst in fructose dehydration reaction in water solvent by ion-doping. Catalysis Today, 192(1), 89-95. doi:10.1016/j.cattod.2011.12.014CARNITI, P., GERVASINI, A., BIELLA, S., & AUROUX, A. (2006). Niobic acid and niobium phosphate as highly acidic viable catalysts in aqueous medium: Fructose dehydration reaction. Catalysis Today, 118(3-4), 373-378. doi:10.1016/j.cattod.2006.07.024Omata, K., Izumi, S., Murayama, T., & Ueda, W. (2013). Hydrothermal synthesis of W–Nb complex metal oxides and their application to catalytic dehydration of glycerol to acrolein. Catalysis Today, 201, 7-11. doi:10.1016/j.cattod.2012.06.004García-Sancho, C., Cecilia, J. A., Moreno-Ruiz, A., Mérida-Robles, J. M., Santamaría-González, J., Moreno-Tost, R., & Maireles-Torres, P. (2015). Influence of the niobium supported species on the catalytic dehydration of glycerol to acrolein. Applied Catalysis B: Environmental, 179, 139-149. doi:10.1016/j.apcatb.2015.05.014Silva, Â., Wilson, K., Lee, A. F., dos Santos, V. C., Cons Bacilla, A. C., Mantovani, K. M., & Nakagaki, S. (2017). Nb2O5/SBA-15 catalyzed propanoic acid esterification. Applied Catalysis B: Environmental, 205, 498-504. doi:10.1016/j.apcatb.2016.12.066Noronha, F. ., Aranda, D. A. ., Ordine, A. ., & Schmal, M. (2000). The promoting effect of Nb2O5 addition to Pd/Al2O3 catalysts on propane oxidation. Catalysis Today, 57(3-4), 275-282. doi:10.1016/s0920-5861(99)00337-5Molina, M. J. C., Granados, M. L., Gervasini, A., & Carniti, P. (2015). Exploitment of niobium oxide effective acidity for xylose dehydration to furfural. Catalysis Today, 254, 90-98. doi:10.1016/j.cattod.2015.01.018Stošić, D., Bennici, S., Rakić, V., & Auroux, A. (2012). CeO2–Nb2O5 mixed oxide catalysts: Preparation, characterization and catalytic activity in fructose dehydration reaction. 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Determination of Integrated Molar Extinction Coefficients for Infrared Absorption Bands of Pyridine Adsorbed on Solid Acid Catalysts. Journal of Catalysis, 141(2), 347-354. doi:10.1006/jcat.1993.1145Oberhauser, W., Evangelisti, C., Jumde, R. P., Psaro, R., Vizza, F., Bevilacqua, M., … Serp, P. (2015). Platinum on carbonaceous supports for glycerol hydrogenolysis: Support effect. Journal of Catalysis, 325, 111-117. doi:10.1016/j.jcat.2015.03.003Oberhauser, W., Evangelisti, C., Tiozzo, C., Vizza, F., & Psaro, R. (2016). Lactic Acid from Glycerol by Ethylene-Stabilized Platinum-Nanoparticles. ACS Catalysis, 6(3), 1671-1674. doi:10.1021/acscatal.5b02914La Salvia, N., Delgado, D., Ruiz-Rodríguez, L., Nadji, L., Massó, A., & Nieto, J. M. L. (2017). V- and Nb-containing tungsten bronzes catalysts for the aerobic transformation of ethanol and glycerol. Bulk and supported materials. Catalysis Today, 296, 2-9. doi:10.1016/j.cattod.2017.04.009Fernández-Arroyo, A., Delgado, D., Domine, M. E., & López-Nieto, J. M. (2017). Upgrading of oxygenated compounds present in aqueous biomass-derived feedstocks over NbOx-based catalysts. Catalysis Science & Technology, 7(23), 5495-5499. doi:10.1039/c7cy00916jShannon, R. D. (1976). Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides. Acta Crystallographica Section A, 32(5), 751-767. doi:10.1107/s0567739476001551Botella, P., Solsona, B., López Nieto, J. M., Concepción, P., Jordá, J. L., & Doménech-Carbó, M. T. (2010). Mo–W-containing tetragonal tungsten bronzes through isomorphic substitution of molybdenum by tungsten. Catalysis Today, 158(1-2), 162-169. doi:10.1016/j.cattod.2010.05.024Jehng, J. M., & Wachs, I. E. (1991). Structural chemistry and Raman spectra of niobium oxides. Chemistry of Materials, 3(1), 100-107. doi:10.1021/cm00013a025Delgado, D., Fernández-Arroyo, A., Domine, M. E., García-González, E., & López Nieto, J. M. (2019). 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Meet OLAF, a Good Friend of the IAPS! The Open Library of Affective Foods: A Tool to Investigate the Emotional Impact of Food in Adolescents

Datos del estudio disponibles en: http://dx.doi.org/10.5281/zenodo.10202In the last decades, food pictures have been repeatedly employed to investigate the emotional impact of food on healthy participants as well as individuals who suffer from eating disorders and obesity. However, despite their widespread use, food pictures are typically selected according to each researcher's personal criteria, which make it difficult to reliably select food images and to compare results across different studies and laboratories. Therefore, to study affective reactions to food, it becomes pivotal to identify the emotional impact of specific food images based on wider samples of individuals. In the present paper we introduce the Open Library of Affective Foods (OLAF), which is a set of original food pictures created to reliably select food pictures based on the emotions they prompt, as indicated by affective ratings of valence, arousal, and dominance and by an additional food craving scale. OLAF images were designed to allow simultaneous use with affective images from the International Affective Picture System (IAPS), which is a well-known instrument to investigate emotional reactions in the laboratory. The ultimate goal of the OLAF is to contribute to understanding how food is emotionally processed in healthy individuals and in patients who suffer from eating and weight-related disorders. The present normative data, which was based on a large sample of an adolescent population, indicate that when viewing affective non-food IAPS images, valence, arousal, and dominance ratings were in line with expected patterns based on previous emotion research. Moreover, when viewing food pictures, affective and food craving ratings were consistent with research on food cue processing. As a whole, the data supported the methodological and theoretical reliability of the OLAF ratings, therefore providing researchers with a standardized tool to reliably investigate the emotional and motivational significance of food.This research was funded by a grant from Junta de Andalucía (Spain) to MCFS (grant code P12.SEJ.391). (http://www.juntadeandalucia.es/servicios​/ayudas/detalle/69962.html; Convocatoria 2012

Cr(VI) sorption/desorption on untreated and mussel-shell-treated soil materials: fractionation and effects of pH and chromium concentration

We used batch-type experiments to study Cr(VI) sorption/desorption on granitic material, forest soil, pyritic material, mussel shell, and on forest soil and granitic material amended with 12 t ha−1 (1.2 kg m −2) shell, considering the effects of varying Cr(VI) concentration and pH. Sequential extractions were carried out to fractionate adsorbed Cr(VI) and to determine the stability of Cr(VI) retention. The pyritic material had the highest Cr(VI) retention capacity, whereas the granitic material showed the lowest retention potential. When high Cr concentrations were added, some saturation of the adsorbent surfaces became apparent, but Cr release remained low. The highest Cr retention was achieved at a very acid pH value, with release progressively increasing as a function of increasing pH. The amendment with 12 t ha−1 mussel shell did not cause marked changes in Cr(VI) retention. Sorption data were satisfactory adjusted to the Freundlich model. Regarding Cr(VI) fractionation, the soluble fraction (weakly bound) was dominant in mussel shell and in the unamended and amended granitic material, whereas more stable fractions dominated in the pyritic material (residual fraction) and in the forest soil (oxidizable fraction). In conclusion, the pyritic material presented the highest Cr(VI) retention capacity, while the retention was low and weak on the granitic material; mussel shell was not characterized by a marked Cr(VI) retention potential, and it did not cause remarkable increase in Cr(VI) retention when used to amend the granitic material or the forest soil.This study was funded by the Ministerio de Economía y Competitividad (Government of Spain), grant numbers CGL2012-36805-C02-01-02S

Metais pesados em solos de pastagem da A Pastoriza (NO Espanha) tratados com chorume de vaca e adubos NPK

In Galicia (NW Spain), pasturelands cover a broad extension and are mainly used to feed cattle. Farms are managed in an intensive manner, using cattle slurry and inorganic fertilizers to increase pasture production, but also increasing risks of heavy metal pollution. In this work we studied the influence of fertilization practices on total concentrations and in-depth distribution of heavy metals and related elements (As, Cd, Cr, Cu, Mn, Ni, Pb and Zn) in two forest soils (SN1, SN2) and five pastureland soils (P1-P5) fertilized with cattle slurry and NPK, in a broadly exploded farmland area (A Pastoriza, Lugo). Soils SN2 and P4 were developed over slate, whereas soils SN1, P1, P2, P3 and P5 evolved on Candana quartzite. Forest soils presented acid pH (4.58-4.68), high Al saturation (75-90%), and low available P concentration (4.78-11.96 mg kg-1), whereas those parameters exhibited better scores in the pastureland soils, due to previous amendment and fertilization practices, thus giving pH 5.17-7.02, Al saturation 0.58-59.24%, and available P 5.24-42.07 mg kg-1. Regarding heavy metals, soil depth did not affect significantly to total concentrations, contrary to that happening with parent material, with higher As, Cu, Fe, and Ni concentrations found in soils over slate (possibly due to the presence of pyritic materials). In most cases, heavy metal total concentrations were lower than that considered as reference background levels for soils developed over each of the parent materials, and were always lower than that considered phyto-toxic. In this study, natural soils usually presented heavy metal total contents similar or even higher than that of the fertilized soils (unless Zn in the P4 pastureland), thus indicating that the spread doses of fertilizers did not influence significantly their concentration levels.En Galicia las praderas ocupan una gran extensión, siendo utilizadas principalmente para la alimentación del ganado vacuno destinado tanto a la producción de leche como de carne. Las granjas se manejan de manera intensiva, utilizando fertilizantes inorgánicos y purín de vacuno para aumentar la producción de pastos. Esta práctica puede aumentar el contenido de metales pesados en el suelo. En este trabajo se estudian las concentraciones totales y la distribución en profundidad de metales pesados y elementos afines (As, Cd, Cr, Cu, Mn, Ni, Pb y Zn) en dos suelos forestales (SN1, SN2) y en cinco praderas (P1-P5) fertilizadas con purín de vacuno y NPK en una zona con una gran vocación ganadera (A Pastoriza, Lugo). Se pretende conocer el grado de influencia de la fertilización sobre los niveles de estos elementos. Los suelos elegidos se desarrollaron a partir de pizarras (SN2, P4) y de cuarcitas de la Serie de Cándana (SN1, P1, P2, P3, P5). Los suelos forestales presentaron pH ácido (4,58-4,68), elevada saturación del complejo de cambio por Al (75-90%) y baja concentración de P disponible (4,78-11,96 mg kg-1); estos parámetros mejoran en los suelos de pradera como consecuencia de las enmiendas y fertilizantes aplicados, presentando un pH entre 5,17 y 7,02, una saturación de Al que varía entre 0,58-59,24% y P disponible entre 5,24 y 42,07 mg kg-1. En relación con los metales pesados, la profundidad de la muestra no afecta de modo significativo a su concentración total, pero sí el material de partida, presentando concentraciones más elevadas de Fe, As, Cu y Ni los suelos desarrollados sobre pizarras, posiblemente debido a la presencia de materiales piríticos. En la mayoría de los casos, los metales pesados estudiados presentan concentraciones totales inferiores a las establecidas como genéricas para suelos desarrollados sobre los respectivos materiales geológicos, y siempre son menores que los límites considerados fitotóxicos. La fertilización aplicada no parece tener una influencia significativa sobre los contenidos totales de estos elementos, con la excepción del Zn en la pradera P4, ya que los suelos naturales en muchos casos presentan valores similares e incluso superiores a los obtenidos en las parcelas fertilizadas.As pastagens ocupam uma grande área na região da Galicia (NO Espanha) destnando-se sobretudo à alimentação de bovinos para produção de leite e carne. As explorações são geridas de forma intensiva, aplicando-se adubos minerais e chorumes com o objetivo de aumentar a produção de pastos. Contudo, esta prática pode aumentar o teor de metais pesados no solo. Neste trabalho, a concentração total e a distribuição em profundidade de metais pesados e elementos associados (As, Cd, Cr, Cu, Mn, Ni, Pb e Zn) foram estudados em dois solos florestais (SN1, SN2) em cinco talhões (P1-P5) adubados com NPK e chorume de bovino, numa área com uma grande vocação para pecuária (A Pastoriza, Lugo). Teve-se por objetivo principal determinar o grau de influência da fertilização nos teores destes elementos. Os solos selecionados foram desenvolvidos a partir de ardósias (SN2, P4) e quartzitos da Série de Candana (SN1, P1, P2, P3, P5). Os solos florestais apresentavam pH ácido (4,58-4,68), alta saturação de Al (75-90%) no complexo de troca de e baixa concentração de P disponível (4,78-11,96 mg kg-1); estes parâmetros melhoram em solos de pastagem, como resultado da calagem e fertilizantes aplicados, apresentando um pH entre 5,17 e 7,02; saturação por Al variando de 0,58 a 59,24% e P disponível entre 5,24 e 42,07 mg kg-1. Em relação aos metais pesados, a profundidade da amostra não afetou significativamente a sua concentração total, contrariamente ao que se verificou com o material parental, que apresentou as concentrações mais elevadas de Fe, As, Cu e Ni nos solos desenvolvidos a partir de ardósias possivelmente devido à presença de materiais piríticos. Na maioria dos casos, os metais pesados estudados apresentaram concentrações totais inferiores aos valores geralmente considerados como referência para solos desenvolvidos a partir dos respetivos materiais parentais, sendo sempre inferiores aos valores limite considerados fitotóxicos. Neste estudo, os solos naturais apresentaram valores de metais pesados semelhantes ou mesmo superiores aos dos solos fertilizados (exceto para o Zn na pastagem P4), o que indica que as doses aplicadas de fertilizantes não influenciaram de forma significativa os seus níveis de concentração.This work was funded by the Spanish Ministerio de Economía y Competitividad (Grant Reference: CGL2012-36805-C02-01)S

Microbial dysbiosis and lack of SCFA production in a Spanish cohort of patients with multiple sclerosis

Background: Multiple sclerosis (MS) is a chronic, demyelinating, and immune-mediated disease of the central nervous system caused by a combination of genetic, epigenetic, and environmental factors. The incidence of MS has increased in the past several decades, suggesting changes in the environmental risk factors. Much effort has been made in the description of the gut microbiota in MS; however, little is known about the dysbiosis on its function. The microbiota produces thousands of biologically active substances among which are notable the short-chain fatty acid (SCFA) excretion. Objectives: Analyze the interaction between microbiota, SCFAs, diet, and MS. Methods: 16S, nutritional questionnaires, and SCFAS quantification have been recovered from MS patients and controls. Results: Our results revealed an increment in the phylum Proteobacteria, especially the family Enterobacteriaceae, a lack in total SCFA excretion, and an altered profile of SCFAs in a Spanish cohort of MS patients. These alterations are more evident in patients with higher disability. Conclusions: The abundance of Proteobacteria and acetate and the low excretion of total SCFAs, especially butyrate, are common characteristics of MS patients, and besides, both are associated with a worse prognosis of the disease.This work was supported by the Spanish Network of Multiple Sclerosis (REEM) under the grant (BIOD19-021) and by Basque government projects (2018111038 and 2019111013)

Entrevista a Dña. Mª Isabel Celaá Diéguez, ministra de Educación y Formación Profesional de España

Isabel Celaá Diéguez has a degree in Philosophy and Letters in the specialty of English Philology, a degree in Law and professor of Baccalaureate in the specialty of English. She has been a teacher for several years; She has held many different elected positions with which she has accumulated extensive management experience, preferably focused on the field of Education. She is currently Minister of Education and Vocational Training of the Government of Spain since June 7, 2018. In her mandate, Organic Law 3/2020, of December 29, has been approved, which modifies Organic Law 2/2006, of May 3, Education, also called LOMLOE and in some areas known as the Celaá law. Recently, she has presented to the Council of Ministers in first reading the text of the Draft Organic Law for the Organization and Integration of Vocational Training. The editorial team of the magazine “Advances in Educational Supervision” wanted to know first-hand the response to different concerns raised by the new law, but not without first congratulating it for having obtained its approval.Isabel Celaá Diéguez es licenciada en Filosofía y Letras en la especialidad de Filología Inglesa, licenciada en Derecho y catedrática numeraria de Bachillerato de la especialidad de inglés. Ha ejercido como profesora durante varios años; ha ocupado muchos y diferentes cargos electos y de designación con los que ha acumulado una amplísima experiencia de gestión centrada preferentemente en el ámbito de la Educación. Actualmente es Ministra de Educación y Formación Profesional del Gobierno de España desde el 7 de junio de 2018. En su mandato se ha aprobado la Ley Orgánica 3/2020, de 29 de diciembre, por la que se modifica la Ley Orgánica 2/2006, de 3 de mayo, de Educación, también denominada LOMLOE y en algunos ámbitos conocida como ley Celaá. Recientemente, ha presentado al Consejo de Ministros en primera lectura el texto de Anteproyecto de Ley Orgánica de Ordenación e Integración de la Formación Profesional. El equipo editorial de la revista “Avances en supervisión Educativa” ha querido conocer de primera mano la respuesta a diferentes inquietudes que suscita la nueva ley no sin antes felicitarla por haber conseguido su aprobación

Enmienda de un suelo de mina con subproductos : efecto sobre la biomasa microbiana determinada mediante el uso de los ácidos grasos de los fosfolípidos

In the present work, the effect of two by-products (pine bark and crushed mussel shell) on microbial biomass and community structure was studied in a soil from a mine tailing located in a copper mine. In a laboratory experiment, different doses (0, 12, 24, 48, 96 and 192 Mg ha-1) of pine bark, crushed mussel shell or mixtures of both by-products were added to the soil. The amended soil samples were incubated for one year at 60% of water holding capacity, and then 33 phospholipid fatty acids (PLFAs) were extracted from these samples and quantified. The PLFAs concentrations were used for different microbial biomass estimations: total biomass, bacterial biomass, fungal biomass, gram-positive (G+) biomass and gram-negative (G-) biomass. The addition of crushed mussel had no significant effects on the total soil microbial biomass, either bacterial of fungal biomass. However, the addition of pine bark increased the total microbial biomass in the soil (up to 40%), mainly due to increases in the fungal biomass (it increased 1600%). No synergistic effects were observed when the soil was amended with both, pine bark and crushed mussel shell. The main community structure changes were due to the addition of pine bark to the soil, and were also due to modifications in fungal communities. Our results suggest that the microbial biomass was mainly limited in the mine soil by low organic matter concentrations, and therefore, practices increasing the amount of soil organic matter should be priorities for soil reclamation.En el presente trabajo se estudió el efecto de dos subproductos (corteza de pino y concha de mejillón triturada) sobre la biomasa y estructura microbiana de un suelo procedente de una escombrera localizada en una mina de cobre. En un experimento realizado en laboratorio fueron añadidas al suelo diferentes dosis (0, 12, 24, 48, 96 and 192 Mg ha-1) de corteza de pino, concha de mejillón triturada y mezclas de ambos subproductos. Las muestras de suelo enmendado fueron incubadas durante un año al 60% de la capacidad de campo, y posteriormente 33 ácidos grasos de los fosfolípidos (PLFAs) fueron extraídos de estas muestras y cuantificados. La concentración de PLFAs fue utilizada para realizar distintas estimaciones de la biomasa microbiana: biomasa total, biomasa bacteriana, biomasa fúngica, biomasa de bacterias gram + y biomasa de bacterias gram -. La adición de concha de mejillón triturada no tuvo efectos significativos sobre la biomasa total ni sobre la biomasa bacteriana o fúngica. Sin embargo, la adición de corteza de pino al suelo incrementó la biomasa total del suelo (hasta un 40%), debido mayormente al incremento de la biomasa fúngica (se incrementó un 1600%). Tampoco se observaron efectos sinérgicos cuando el suelo fue enmendado con una mezcla de corteza de pino y concha de mejillón triturada. Los mayores cambios en la estructura de las comunidades microbianas fueron debidos a la adición de corteza de pino al suelo, y fueron además debidas a cambios en las comunidades fúngicas. Nuestros resultados sugieren que la biomasa microbiana del suelo de mina está mayormente limitada por la concentración de materia orgánica y, por tanto, deben ser priorizadas prácticas de manejo que contribuyan a incrementarla para la rehabilitación de este tipo de suelos.Neste trabalho foi estudado o efeito de dois subprodutos (casca de pinheiro e concha de mexilhão triturada) na biomassa e estrutura microbiana de um solo procedente de uma escombreira localizada numa mina de cobre. Numa experiência de laboratório, doses diferentes (0, 12, 24, 48, 96 e 192 Mg ha-1) de casca de pinheiro, concha de mexilhão triturada e misturas de ambos os subprodutos foram adicionados ao solo. Amostras de solo corrigido com os resíduos foram incubadas durante um ano a 60% da sua capacidade de retenção de água, e subsequentemente, 33 ácidos gordos dos fosfolípidos (PLFAs) foram extraídos a partir destas amostras e quantificados. A concentração de PLFAs foi usada para estimar vários tipos de biomassa microbiana: biomassa total, biomassa bacteriana, biomassa fúngica, biomassa de bactérias gram positivas e biomassa de bactérias gram negativas. A adição de concha de mexilhão triturada não teve nenhum efeito significativo na biomassa total ou na biomassa bacteriana ou fúngica. Porém, a adição de casca de pinheiro aumentou a biomassa microbiana do solo (até 40%), principalmente devido ao aumento da biomassa fúngica (a qual aumentou de 1600%). Não foi observado nenhum efeito de sinergismo quando o solo foi corrigido com uma mistura de casca de pinheiro e concha de mexilhão triturada. As maiores alterações na estrutura das comunidades microbianas foram produzidas pela adição de casca de pinheiro ao solo, as quais resultaram em alterações nas comunidades fúngicas. Os resultados sugerem que a biomassa microbiana do solo de mina é, maioritariamente limitada pela concentração de matéria orgânica. Assim, práticas que contribuam para o seu aumento devem ser prioritárias para a reabilitação deste tipo de solos